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HRID1941840

反应详情

EQUATION

反应方程式

HRID 1941840 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1ncccc1OCC(F)(F)F
HCID57475879

未命名化合物

结构：C[C@]1(c2cc(N)ccc2F)N=C(N)OCC1(F)F
HCID58304207

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]1(c2cc(NC(=O)c3ncccc3OCC(F)(F)F)ccc2F)N=C(N)OCC1(F)F
HCID53241005

未命名化合物

PROCEDURE

实验过程

The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-1) and 3-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid following procedure I yielded the title compound. MS (ISP): m/z=463.1 [M+H]+. The 3-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid was prepared as follows: