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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1941845Generated: October 31, 2026

HCID 11062693, compound → HCID 53241102, compound

https://huagongshe.com/reaction/1941845

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11062693HCID 11062693—
Reactant(R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamineHCID 58304207—
ProductHCID 53241102HCID 53241102—

Reaction Steps

The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-1) and 2-chloromethyl-oxazole-4-carboxylic acid following procedure I yielded the title compound as a colorless viscous oil. MS (ISP): m/z=403.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389513B2
Source datasetuspto-grants-2013_03
ORD IDord-83e425407743487b8d7c95d67a98583a
Source noteuspto-grants-2013_03