HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 19619548, compound → HCID 53241399, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 19619548 | HCID 19619548 | — |
| Reactant | (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine | HCID 58304207 | — |
| Product | HCID 53241399 | HCID 53241399 | — |
Reaction Steps
The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-1) and 4-chloro-1-(2,2,2-trifluoro-ethyl)-1H-pyrazole-3-carboxylic acid (CAS1006448-63-0) following procedure I yielded the title compound as a white solid. MS (ISP): m/z=470.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389513B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-c22f7eb166664105b182e3dfc1352cef |
| Source note | uspto-grants-2013_03 |