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HRID1941869

反应详情

EQUATION

反应方程式

HRID 1941869 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)/C=C/c1ccco1
HCID643402

(E)-2-Furanacrylic acid

C7H6O3

结构：C[C@]1(c2cc(N)ccc2F)N=C(N)OCC1(F)F
HCID58304207

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]1(c2cc(NC(=O)/C=C/c3ccco3)ccc2F)N=C(N)OCC1(F)F
HCID53241493

未命名化合物

PROCEDURE

实验过程

The condensation of (R)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-ylamine (intermediate XI-1) and (E)-3-furan-2-yl-acrylic acid following procedure I yielded the title compound after purification by preparative HPLC. MS (ISP): m/z=380.1 [M+H]+.