反应详情

The title compound was prepared analogy to Example 38 using 6-chloro-3-[(S)-1-(6-fluoro-1-methyl-1H-indazol-5-yl)-ethyl]-imidazo[1,2-b]pyridazine (Intermediate E) (50 mg, 0.153 mmol) and 1-acetylpiperazine (39.2 mg, 0.306 mmol) (tR 3.67 min (conditions 5), MH+=421, 1H-NMR in DMSO-d6: 7.93 (s, 1H); 7.81 (d, 1H); 7.52 (d, 1H); 7.50 (s, 1H); 7.47 (d, 1H); 4.75 (m, 1H); 3.95 (s, 3H); 3.42 (m, 6H); 2.00 (s, 3H); 1.70 (d, 3H)).