反应详情

The title compound was prepared in analogy to Example 52 using 6-chloro-3-((4,6-difluoro-1-methyl-1H-indazol-5-yl)methyl)imidazo[1,2-b]pyridazine (Intermediate T, (100 mg, 0.300 mmol) and piperazin-2-one (90 mg, 0.899 mmol) (tR 3.47 min (conditions 4), MH+=398, 1H-NMR in DMSO-d6: 8.13 (s, 1H); 8.11 (s, 1H); 7.81 (d, 1H); 7.45 (d, 1H); 7.27 (s, 1H); 7.09 (d, 1H), 4.27 (s, 2H); 3.98 (m, 5H); 3.67 (m, 2H), 3.29 (m, 2H)).