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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1942202Generated: November 2, 2026

5,5-Dimethylpiperidin-2-one → 5,5-Dimethyl-1-(5-phenylethynyl-pyridin-2-ylmethyl)-piperidin-2-one

https://huagongshe.com/reaction/1942202

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,5-Dimethylpiperidin-2-oneHCID 10479660—
Reactant(5-Phenylethynyl-pyridin-2-yl)-methanolHCID 57517077—
Product5,5-Dimethyl-1-(5-phenylethynyl-pyridin-2-ylmethyl)-piperidin-2-oneHCID 52917194—

Reaction Steps

The title compound, yellow oil, MS: m/e=319.2 (M+H+), can be prepared in accordance with the general method of example 31, step 2 from (5-phenylethynyl-pyridin-2-yl)-methanol (example 31, step 1) and 5,5-dimethyl-piperidin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389536B2
Source datasetuspto-grants-2013_03
ORD IDord-f6546e15d2544f8898ab732c720d7f0f
Source noteuspto-grants-2013_03