(5-Methyl-3-phenyl-1,2-oxazol-4-yl)methanol → 5-Methyl-3-phenylisoxazole-4-carboxaldehyde

Participants

Reaction Steps

To a solution of (5-methyl-3-phenyl-4-isoxazolyl)methanol (8.0 g, 42 mmol) in dichloromethane (1 L) was added manganese(IV) oxide (81.7 g, 0.85 mol) and the resulting mixture stirred vigorously for 7 days. The mixture was then filtered and the filtrate evaporated to afford the title compound (7.1 g, 89%) as a light yellow solid. MS: m/e=188.2 [M+H]+.

Provenance & Evidence