2-Aminopropanol → HCID 46872637, compound

Participants

Reaction Steps

As described in example 10, 6-[(E)-2-(3-butyl-5-methyl-isoxazol-4-yl)-vinyl]-nicotinic acid methyl ester (100 mg, 0.28 mmol), and L-2-amino-1-propanol instead of DL-2-amino-1-propanol, was converted to the title compound (41 mg, 36%) which was obtained as a colorless oil after purification by chromatography (silica, dichloromethane:methanol 100:0 to 96.5:3.5). MS: m/e=364.4 [M+H]+.

Provenance & Evidence