4-Amino-1-butanol → Naphthalene-2-carboxylic acid (4-hydroxy-butyl)-amide

Participants

Reaction Steps

43 mmol (8.2 g) naphthalen-2-carboxylic acid chloride is dissolved in 50 mL dioxane and dropwise added to a solution of 112 mmol (10.0 g) 4-amino-butan-1-ol in 100 mL dioxane and stirred overnight at room temperature. The mixture is then poured into 200 mL of ice water and filtrated. The white solid separated is dried under vacuum.

Provenance & Evidence