N-methyl-1,4-dioxaspiro(4.5)decan-8-amine → N6-Methyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine dihydrobromide

HRID 1942341Notes

Reaction equation

HRID 1942341 reaction equation
O1C2(CCC(NC)CC2)OCC1.[BrH:13].Br.[CH2:15]([NH:18][CH:19]1[CH2:28][CH2:27][C:22]2[N:23]=[C:24]([NH2:26])[S:25][C:21]=2[CH2:20]1)CC>>[BrH:13].[BrH:13].[CH3:15][NH:18][CH:19]1[CH2:28][CH2:27][C:22]2[N:23]=[C:24]([NH2:26])[S:25][C:21]=2[CH2:20]1

Participants

3

Reactant 2

HCID 16786570N-methyl-1,4-dioxaspiro(4.5)decan-8-amineHCID 86651296N6-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine dihydrobromide

Product 1

HCID 13670705N6-Methyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine dihydrobromideYield 62%

Procedure

N6-Methyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine dihydrobromide (3B) is prepared from 3A as described for 1B.

Sources & evidence

ORD record
ord-dcbfad4e068e4127b7e6d66c14cabb46
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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