N6-Methyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine dihydrobromide → Etrabamine

HRID 1942342Notes

Reaction equation

HRID 1942342 reaction equation
Br.Br.[CH3:3][NH:4][CH:5]1[CH2:14][CH2:13][C:8]2[N:9]=[C:10](N)[S:11][C:7]=2[CH2:6]1.C(NC1CCC2N=CSC=2C1)CC>>[CH3:3][NH:4][CH:5]1[CH2:14][CH2:13][C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6]1

Participants

3

Reactant 2

HCID 13670705N6-Methyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine dihydrobromideHCID 18705889Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine

Product 1

HCID 68895EtrabamineYield 40%

Procedure

Methyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine (3C) is prepared from 3B as described for 1C.

Sources & evidence

ORD record
ord-5bcfbcb0a5a9431c909e47612e13c7ca
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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