Etrabamine → Naphthalene-2-carboxylic acid {4-[methyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-butyl}-amide

Participants

Role	Name	HCID	Charge
Reactant	Etrabamine	HCID 68895	—
Reactant	Naphthalene-2-carboxylic acid (4-oxo-butyl)-amide	HCID 86651298	—
Product	Naphthalene-2-carboxylic acid {4-[methyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-butyl}-amide	HCID 66937345	25%

Compound 3 is prepared from 2E and 3C as described for 1. The resulting oil is crystallized as salt of oxalic acid from ethanol/diethylether.