Ethylamine → N-ethyl-1,4-dioxaspiro[4.5]decan-8-amine

HRID 1942344Notes

Reaction equation

HRID 1942344 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([NH:11][CH2:12][CH2:13]C)[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.C(N)C>>[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([NH:11][CH2:12][CH3:13])[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 6341EthylamineHCID 118200814-n-Propylamino-cyclohexanone-ethyleneketal

Product 1

HCID 15342646N-ethyl-1,4-dioxaspiro[4.5]decan-8-amine

Procedure

(1,4-Dioxa-spiro[4.5]dec-8-yl)-ethylamine (4A) is prepared operating as described for 1A with 7.85 mL (120 mmol) of cooled liquid ethylamine.

Sources & evidence

ORD record
ord-32059274e0234b869c3c8c9a486de5bb
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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