Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine → HCID 66937549, compound
Reaction equation
[CH2:1]([NH:4][CH:5]1[CH2:13][CH2:12][C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6]1)CC.O=[CH:15][CH2:16][CH2:17][CH2:18][NH:19][C:20]([C:22]1[S:26][C:25]2[CH:27]=[CH:28][CH:29]=[CH:30][C:24]=2[CH:23]=1)=[O:21]>>[CH3:1][N:4]([CH:5]1[CH2:13][CH2:12][C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6]1)[CH2:15][CH2:16][CH2:17][CH2:18][NH:19][C:20]([C:22]1[S:26][C:25]2[CH:27]=[CH:28][CH:29]=[CH:30][C:24]=2[CH:23]=1)=[O:21]Participants
3
Procedure
Compound 11 is prepared as described for 1 from 1C and 11A. The salt of oxalic acid is crystallized from ethanol/diethylether.
Workup
- customThe salt of oxalic acid is crystallized from ethanol/diethylether
Sources & evidence
- ORD record
- ord-24002f03f1d54beeae285d07d712da31
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08389555B2
Reaction notes
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