1,2,3,4-Tetrahydronaphthalene-2-carbonyl chloride → 1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4,4-diethoxy-butyl)-amide
Reaction equation
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[C:11](Cl)=[O:12].[CH2:14]([O:16][CH:17]([O:30][CH2:31][CH3:32])[CH2:18][CH2:19][CH2:20][NH:21]C(C1CCCCC1)=O)[CH3:15]>>[CH2:31]([O:30][CH:17]([O:16][CH2:14][CH3:15])[CH2:18][CH2:19][CH2:20][NH:21][C:11]([CH:2]1[CH2:3][CH2:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH2:1]1)=[O:12])[CH3:32]Participants
3
Procedure
1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4,4-diethoxy-butyl)-amide (23B) is prepared from 23A as described for 20A.
Sources & evidence
- ORD record
- ord-5f59b2e83fb74963a26006ba550b5314
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08389555B2
Reaction notes
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