1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4,4-diethoxy-butyl)-amide → 1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4-oxo-butyl)-amide

HRID 1942353Notes

Reaction equation

HRID 1942353 reaction equation
C([O:3][CH:4](OCC)[CH2:5][CH2:6][CH2:7][NH:8][C:9]([CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)=[O:10])C.O=CCCCNC(C1CCCCC1)=O>>[O:3]=[CH:4][CH2:5][CH2:6][CH2:7][NH:8][C:9]([CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)=[O:10]

Participants

3

Procedure

1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4-oxo-butyl)-amide (23C) is prepared from 23B as described for 20B.

Sources & evidence

ORD record
ord-471fb219b49e4cd781a1404039400ca1
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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