1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4,4-diethoxy-butyl)-amide → 1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4-oxo-butyl)-amide
Reaction equation
C([O:3][CH:4](OCC)[CH2:5][CH2:6][CH2:7][NH:8][C:9]([CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)=[O:10])C.O=CCCCNC(C1CCCCC1)=O>>[O:3]=[CH:4][CH2:5][CH2:6][CH2:7][NH:8][C:9]([CH:11]1[CH2:20][CH2:19][C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12]1)=[O:10]Participants
3
Procedure
1,2,3,4-Tetrahydro-naphthalene-2-carboxylic acid (4-oxo-butyl)-amide (23C) is prepared from 23B as described for 20B.
Sources & evidence
- ORD record
- ord-471fb219b49e4cd781a1404039400ca1
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08389555B2
Reaction notes
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