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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1942357Generated: November 3, 2026

Benzamide, N-(4-hydroxybutyl)- → 6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-hydroxy-butyl)-amide

https://huagongshe.com/reaction/1942357

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzamide, N-(4-hydroxybutyl)-HCID 11217773—
Reactant6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl chlorideHCID 79886110—
Product6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-hydroxy-butyl)-amideHCID 6693754067%

Reaction Steps

6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid (4-hydroxy-butyl)-amide (25B) is prepared from 25A as described for 1D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389555B2
Source datasetuspto-grants-2013_03
ORD IDord-b39c384e25c8491db227796022b2936c
Source noteuspto-grants-2013_03