Benzamide, N-(4-hydroxybutyl)- → 1-(4-Hydroxybutyl)-3-indan-2-ylurea

HRID 1942369Notes

Reaction equation

HRID 1942369 reaction equation
[N:1]([CH:4]1[CH2:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5]1)=[C:2]=[O:3].[OH:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18]C(=O)C1C=CC=CC=1>>[OH:13][CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:2]([NH:1][CH:4]1[CH2:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5]1)=[O:3]

Participants

3

Reactant 2

HCID 11217773Benzamide, N-(4-hydroxybutyl)-HCID 578841982-isocyanato-2,3-dihydro-1H-indene

Product 1

HCID 669376021-(4-Hydroxybutyl)-3-indan-2-ylureaYield 61%

Procedure

1-(4-Hydroxybutyl)-3-indan-2-ylurea (60B) is prepared from 60A as described for 1D.

Sources & evidence

ORD record
ord-e343800f26f5490c85471e663c587a02
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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