N-(4-oxo-butyl)-benzamide → 4-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid (4-oxobutyl)amide

HRID 1942377Notes

Reaction equation

HRID 1942377 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][NH:6][C:7]([N:9]1[CH2:14][CH:13]=[C:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:11][CH2:10]1)=[O:8].O=CCCCNC(=O)C1C=CC=CC=1>>[O:1]=[CH:2][CH2:3][CH2:4][CH2:5][NH:6][C:7]([N:9]1[CH2:10][CH:11]=[C:12]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH2:13][CH2:14]1)=[O:8]

Participants

3

Reactant 2

HCID 10352536N-(4-oxo-butyl)-benzamideHCID 669374264-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid (4-hydroxybutyl)amide

Product 1

HCID 866513104-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid (4-oxobutyl)amide

Procedure

4-Phenyl-3,6-dihydro-2H-pyridine-1-carboxylic acid (4-oxobutyl)amide (62C) is prepared from 62B as described for 1E. The product is obtained in almost quantitative yield.

Workup

  1. customThe product is obtained in almost quantitative yield

Sources & evidence

ORD record
ord-17d40a8b46fd4600bd81942200d1b90f
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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