HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → N-(4-hydroxybutyl)benzothiazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Amino-1-butanol | HCID 25868 | — |
| Reactant | Benzothiazole-2-carbonyl chloride | HCID 2776254 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | N-(4-hydroxybutyl)benzothiazole-2-carboxamide | HCID 66937473 | — |
Reaction Steps
1 g (5 mmol) benzothiazol-2-carbonyl chloride, 542 mg (6 mmol) 4-aminobutan-1-ol and 1.4 g (10 mmol) K2CO3 in acetonitrile is stirred for three days at room temperature. The solvent is evaporated and the product is dissolved in ethyl acetate and washed with 2N HCl and water. After evaporation of the solvent the yellow semisolid is crystallized from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389555B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-9ce5a60c887c4de9a7f58f32a483d012 |
| Source note | uspto-grants-2013_03 |