Benzamide, N-(4-hydroxybutyl)- → N-Propyl-4-{[propyl-(4,5,6,7-tetrahydrobenzothiazol-6-yl)amino]methyl}-N-(4,5,6,7-tetrahydrobenzothiazol-6-yl)benzamide

HRID 1942399Notes

Reaction equation

HRID 1942399 reaction equation
[CH2:1]([N:4]([CH2:14][C:15]1[CH:23]=[CH:22][C:18]([C:19](Cl)=[O:20])=[CH:17][CH:16]=1)[CH:5]1[CH2:13][CH2:12][C:8]2[N:9]=[CH:10][S:11][C:7]=2[CH2:6]1)[CH2:2][CH3:3].OCCCCNC(=O)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH2:1]([N:4]([CH:31]1[CH2:32][CH2:33][C:34]2[N:9]=[CH:10][S:11][C:35]=2[CH2:36]1)[C:19](=[O:20])[C:18]1[CH:22]=[CH:23][C:15]([CH2:14][N:4]([CH2:1][CH2:2][CH3:3])[CH:5]2[CH2:13][CH2:12][C:8]3[N:9]=[CH:10][S:11][C:7]=3[CH2:6]2)=[CH:16][CH:17]=1)[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 11217773Benzamide, N-(4-hydroxybutyl)-HCID 866513144-{[Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amino]-methyl}-benzoyl chloride

Product 1

HCID 66937622N-Propyl-4-{[propyl-(4,5,6,7-tetrahydrobenzothiazol-6-yl)amino]methyl}-N-(4,5,6,7-tetrahydrobenzothiazol-6-yl)benzamideYield 74%

Procedure

Compound 42 is prepared from 42C and IC-CORRECT? as described for 1D.

Sources & evidence

ORD record
ord-1fb7d4494fee4b2f84643e543b7435aa
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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