Propyl-(4,5,6,7-tetrahydro-benzothiazol-6-yl)-amine → HCID 66937470, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH:17]=O)[CH2:11][CH2:10]1.[CH2:19]([NH:22][CH:23]1[CH2:31][CH2:30][C:26]2[N:27]=[CH:28][S:29][C:25]=2[CH2:24]1)[CH2:20]C>>[CH2:19]([N:22]([CH2:17][CH2:16][CH2:15][N:12]1[CH2:13][CH2:14][N:9]([C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=2[O:2][CH3:1])[CH2:10][CH2:11]1)[CH:23]1[CH2:31][CH2:30][C:26]2[N:27]=[CH:28][S:29][C:25]=2[CH2:24]1)[CH3:20]Participants
3
Procedure
Compound 29 is prepared from 29B and 1C as described for 1. The salt of maleic acid is crystallized from ethanol/diethylether.
Workup
- customThe salt of maleic acid is crystallized from ethanol/diethylether
Sources & evidence
- ORD record
- ord-65387ed12fbe46f5aefa960eadf91c53
- Source dataset
- uspto-grants-2013_03
- Patent number
- US08389555B2
Reaction notes
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