2-(3,4-Dihydroisoquinolin-2(1H)-yl)ethanol → (3,4-Dihydro-1H-isoquinolin-2-yl)-acetaldehyde

HRID 1942429Notes

Reaction equation

HRID 1942429 reaction equation
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]1[CH2:11][CH2:12][OH:13].O=CCCCNC(=O)C1C=CC=CC=1>>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]1[CH2:11][CH:12]=[O:13]

Participants

3

Reactant 2

HCID 2462882-(3,4-Dihydroisoquinolin-2(1H)-yl)ethanolHCID 10352536N-(4-oxo-butyl)-benzamide

Product 1

HCID 61740690(3,4-Dihydro-1H-isoquinolin-2-yl)-acetaldehyde

Procedure

(3,4-Dihydro-1H-isoquinolin-2-yl)-acetaldehyde (31B) is prepared from 31A as described for 1E.

Sources & evidence

ORD record
ord-c13fbbfd43e04f3c95a39475f9cc8a6a
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

Loading…