N-(4-oxo-butyl)-benzamide → 4-(2,3-Dichlorophenyl)-1-piperazinepropanal

HRID 1942433Notes

Reaction equation

HRID 1942433 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][CH2:17][OH:18])[CH2:11][CH2:10]1.O=CCCCNC(=O)C1C=CC=CC=1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]1[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][CH:17]=[O:18])[CH2:13][CH2:14]1

Participants

3

Reactant 2

HCID 10352536N-(4-oxo-butyl)-benzamideHCID 210732893-[4-(2,3-Dichlorophenyl)piperazin-1-yl]propan-1-ol

Product 1

HCID 866513174-(2,3-Dichlorophenyl)-1-piperazinepropanal

Procedure

3-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-propionaldehyde (36B) is prepared from 36A as described for 1E.

Sources & evidence

ORD record
ord-06f8c6c2d58f4a5782d308f11aca6c0c
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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