1-Benzoylpiperazine → 2-(4-Benzoylpiperazin-1-yl)ethan-1-ol

HRID 1942436Notes

Reaction equation

HRID 1942436 reaction equation
[C:1]([N:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[O:16][C:17]1C=CC=C[C:18]=1N1CCN(CCO)CC1>>[C:1]([N:9]1[CH2:14][CH2:13][N:12]([CH2:18][CH2:17][OH:16])[CH2:11][CH2:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7626541-BenzoylpiperazineHCID 111073541-Piperazineethanol, 4-(2-methoxyphenyl)-

Product 1

HCID 32616012-(4-Benzoylpiperazin-1-yl)ethan-1-olYield 90%

Procedure

2-(4-Benzoyl-piperazin-1-yl)-ethanol (38A) is prepared from 1-benzoyl-piperazine as described for 28A.

Sources & evidence

ORD record
ord-59b08203164444c78cc5daab82929cf1
Source dataset
uspto-grants-2013_03
Patent number
US08389555B2

Reaction notes

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