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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1942468Generated: November 3, 2026

4-(4-Methoxybutyl)-2,2-dimethyl-3-oxo-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid → HCID 91582039, compound

https://huagongshe.com/reaction/1942468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Methoxybutyl)-2,2-dimethyl-3-oxo-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acidHCID 58375807—
ReactantHCID 67331090HCID 67331090—
ProductHCID 91582039HCID 91582039—

Reaction Steps

Using 4-(4-methoxybutyl)-2,2-dimethyl-3-oxo-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylic acid and tert-butyl (rac.)-(3R,4R)-3-amino-4-benzylpiperidine-1-carboxylate (US 2005/182095), the title compound was obtained in a similar manner to Reference Example 197.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389511B2
Source datasetuspto-grants-2013_03
ORD IDord-4206a294bbe6462584a204be09ea0af0
Source noteuspto-grants-2013_03