HCID 58376062, compound → HCID 67330038, compound

HRID 1942501Notes

Reaction equation

HRID 1942501 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([F:15])=[C:6]([C:8]([OH:14])([CH3:13])[C:9]([O:11]C)=O)[CH:7]=1.F[C:17]1[C:26]([N+:27]([O-])=O)=[CH:25][C:20]([C:21]([O:23][CH3:24])=[O:22])=[C:19]([C:30]([F:33])([F:32])[F:31])[CH:18]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([F:15])=[C:6]([C:8]2([CH3:13])[C:9](=[O:11])[NH:27][C:26]3[CH:25]=[C:20]([C:21]([O:23][CH3:24])=[O:22])[C:19]([C:30]([F:33])([F:31])[F:32])=[CH:18][C:17]=3[O:14]2)[CH:7]=1

Participants

3

Reactant 2

HCID 58376062HCID 58376062, compoundHCID 67331383HCID 67331383, compound

Product 1

HCID 67330038HCID 67330038, compound

Procedure

Using methyl 2-(5-bromo-2-fluorophenyl)-2-hydroxypropanoate and methyl 4-fluoro-5-nitro-2-(trifluoromethyl)benzoate, the title compound was obtained in a similar manner to Reference Example 22 and Reference Example 2.

Sources & evidence

ORD record
ord-b988ad81b545476dbfd2330d462b4533
Source dataset
uspto-grants-2013_03
Patent number
US08389511B2

Reaction notes

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