HCID 54857374, compound → HCID 67330716, compound

HRID 1942502Notes

Reaction equation

HRID 1942502 reaction equation
[OH:1][C:2]([C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([C:14]([F:17])([F:16])[F:15])[CH:9]=1)([CH3:7])[C:3]([O:5]C)=O.F[C:19]1[C:28]([N+:29]([O-])=O)=[CH:27][C:22]([C:23]([O:25][CH3:26])=[O:24])=[C:21]([C:32](F)(F)F)[CH:20]=1>>[CH3:7][C:2]1([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([C:14]([F:17])([F:16])[F:15])[CH:9]=2)[C:3](=[O:5])[NH:29][C:28]2[CH:27]=[C:22]([C:23]([O:25][CH3:26])=[O:24])[C:21]([CH3:32])=[CH:20][C:19]=2[O:1]1

Participants

3

Reactant 2

HCID 54857374HCID 54857374, compoundHCID 58376062HCID 58376062, compound

Product 1

HCID 67330716HCID 67330716, compound

Procedure

Using methyl 2-hydroxy-2-[3-(trifluoromethyl)phenyl]propanoate and methyl 4-fluoro-5-nitro-2-(trifluoromethyl)benzoate, the title compound was obtained in a similar manner to Reference Example 22 and Reference Example 2.

Sources & evidence

ORD record
ord-a37ee6fe9590403e9a1917b75b8500e1
Source dataset
uspto-grants-2013_03
Patent number
US08389511B2

Reaction notes

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