1,1-Dimethylethyl (3S)-3-[(1-methylethyl)amino]-1-piperidinecarboxylate → HCID 86656362, compound

HRID 1942514Notes

Reaction equation

HRID 1942514 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][N:7]1[C:12]2[CH:13]=[C:14]([C:21](OC)=[O:22])[C:15]([C:17]([F:20])([F:19])[F:18])=[CH:16][C:11]=2[O:10][C:9]([CH3:26])([CH3:25])[C:8]1=[O:27].[CH:28]([NH:31][C@H:32]1[CH2:37][CH2:36][CH2:35][N:34]([C:38]([O:40][C:41]([CH3:44])([CH3:43])[CH3:42])=[O:39])[CH2:33]1)([CH3:30])[CH3:29]>>[CH:28]([N:31]([C:21]([C:14]1[C:15]([C:17]([F:20])([F:18])[F:19])=[CH:16][C:11]2[O:10][C:9]([CH3:26])([CH3:25])[C:8](=[O:27])[N:7]([CH2:6][CH2:5][CH2:4][CH2:3][O:2][CH3:1])[C:12]=2[CH:13]=1)=[O:22])[C@H:32]1[CH2:37][CH2:36][CH2:35][N:34]([C:38]([O:40][C:41]([CH3:43])([CH3:42])[CH3:44])=[O:39])[CH2:33]1)([CH3:30])[CH3:29]

Participants

3

Reactant 2

HCID 532569101,1-Dimethylethyl (3S)-3-[(1-methylethyl)amino]-1-piperidinecarboxylateHCID 58376114HCID 58376114, compound

Product 1

HCID 86656362HCID 86656362, compound

Procedure

Using methyl 4-(4-methoxybutyl)-2,2-dimethyl-3-oxo-7-(trifluoromethyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxylate and tert-butyl (3S)-3-(isopropylamino)piperidine-1-carboxylate, the title compound was obtained in a similar manner to Reference Example 5.

Sources & evidence

ORD record
ord-6316c8055f604aebbf5cfa29113cf350
Source dataset
uspto-grants-2013_03
Patent number
US08389511B2

Reaction notes

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