HCID 58376069, compound → HCID 58376482, compound

Participants

Reaction Steps

To a solution of tert-butyl (3R)-3-[[4-(ethylamino)-5-nitro-2-(trifluoromethyl)benzoyl]-(isopropyl)amino]piperidine-1-carboxylate (610 mg) in tetrahydrofuran (10 ml) was added 10% palladium-carbon (600 mg, 50% wet.), and the mixture was stirred at room temperature under hydrogen atmosphere for 3 hours. The reaction solution was filtered on celite, washed with tetrahydrofuran, and the filtrate was concentrated under reduced pressure to give the title compound (550 mg).

Provenance & Evidence