Triethyl phosphite → Phosphonic acid, P-[(3-bromo-2-ethylphenyl)methyl]-, diethyl ester

Participants

Reaction Conditions

Reaction Steps

To a solution of 1-bromo-3-(bromomethyl)-2-ethylbenzene (D134) (1.3 g, 4.68 mmol) in Toluene (10 mL) was added triethyl phosphite (0.818 mL, 4.68 mmol). The reaction solution was heated in a sealed tube at 130° C. for 2 days. The solvent was removed in vacuo to afford diethyl [(3-bromo-2-ethylphenyl)methyl]phosphonate (D135) (1.567 g), which was used directly without further purification. MS (ES): C13H20BrO3P requires 334.0. found 335.0 (M+H+).

Provenance & Evidence