Trifluoroacetic acid → HCID 58494028, compound

Participants

Reaction Steps

To a solution of 1,1-dimethylethyl 4-[(3-bromo-2-ethylphenyl)methylidene]-1-piperidinecarboxylate (D136) (3 g, 7.89 mmol) in Dichloromethane (DCM) (100 mL) was added TFA (6.08 mL, 79 mmol). The reaction solution was stirred at room temperature for 2 hours. The solvent was evaporated in vacuo to afford 4-[(3-bromo-2-ethylphenyl)methylidene]piperidine (D137) (1.9 g), which was used directly without further purification. MS (ES): C14H18BrN requires 279.1. found 280.1 (M+H+).

Provenance & Evidence