Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-{[[(2,4-dinitrophenyl)sulfonyl]({1-[(trimethylsilyl)methyl]-1H-1,2,3-triazol-4-yl}methyl)amino]methyl}benzoate → Methyl 4-{[({1-[(trimethylsilyl)methyl]-1H-1,2,3-triazol-4-yl}methyl)amino]methyl}benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-{[[(2,4-dinitrophenyl)sulfonyl]({1-[(trimethylsilyl)methyl]-1H-1,2,3-triazol-4-yl}methyl)amino]methyl}benzoate | HCID 59627272 | — |
| 용매 | Propylamine | HCID 7852 | — |
| 생성물 | Methyl 4-{[({1-[(trimethylsilyl)methyl]-1H-1,2,3-triazol-4-yl}methyl)amino]methyl}benzoate | HCID 59627278 | — |
반응 단계
Crude methyl 4-{[[(2,4-dinitrophenyl)sulfonyl]({1-[(trimethylsilyl)methyl]-1H-1,2,3-triazol-4-yl}methyl)amino]methyl}benzoate (732 mg, 1.30 mmol) was dissolved in propylamine (2.25 mL) and stirred overnight. The reaction was concentrated and purified via MPLC, 1-8% MeOH in DCM to afford the requisite product as a clear, colorless oil. MS: cal'd 333 (MH+), exp 333 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08389553B2 |
| 출처 데이터셋 | uspto-grants-2013_03 |
| ORD ID | ord-beca3fb32e214ed2bfe60d1980bd2904 |
| 출처 메모 | uspto-grants-2013_03 |