4-Chloroaniline → HCID 45275191, compound

HRID 1942872Notes

Reaction equation

HRID 1942872 reaction equation
Cl[C:2]1[N:7]=[C:6]([O:8][CH3:9])[N:5]=[C:4]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([N:17]3[CH:21]=[C:20]([CH3:22])[N:19]=[CH:18]3)=[C:13]([O:23][CH3:24])[CH:12]=2)[N:3]=1.[Cl:25][C:26]1[CH:32]=[CH:31][C:29]([NH2:30])=[CH:28][CH:27]=1>>[Cl:25][C:26]1[CH:32]=[CH:31][C:29]([NH:30][C:2]2[N:3]=[C:4]([NH:10][C:11]3[CH:16]=[CH:15][C:14]([N:17]4[CH:21]=[C:20]([CH3:22])[N:19]=[CH:18]4)=[C:13]([O:23][CH3:24])[CH:12]=3)[N:5]=[C:6]([O:8][CH3:9])[N:7]=2)=[CH:28][CH:27]=1

Participants

3

Reactant 2

HCID 78124-ChloroanilineHCID 86640783(4-Chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine

Product 1

HCID 45275191HCID 45275191, compoundYield 15%

Procedure

The title compound was prepared from (4-chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine and 4-chloroaniline in analogy to example 1c). It was obtained in 15% yield as a colorless solid.

Workup

  1. customIt was obtained in 15% yield as a colorless solid

Sources & evidence

ORD record
ord-98e0b616a4cd4762b3cce4aba15f3b84
Source dataset
uspto-grants-2013_03
Patent number
US08389717B2

Reaction notes

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