HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 45275076, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | (4-Chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 86640783 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 45275076 | HCID 45275076 | 22% |
Reaction Steps
This compound was prepared from (4-chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine and piperidine in analogy to example 1c. Chromatography on Si—NH2 gel (Isolute) using ethyl acetate as an eluent gave the title compound as a colorless solid in 22% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389717B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-56a2500630e64fe8a5ecb3c8cff968c8 |
| Source note | uspto-grants-2013_03 |