HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichlorophenol → [4-(2,4-Dichloro-phenoxy)-6-methoxy-[1,3,5]triazin-2-yl]-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichlorophenol | HCID 8449 | — |
| Reactant | (4-Chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 86640783 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | [4-(2,4-Dichloro-phenoxy)-6-methoxy-[1,3,5]triazin-2-yl]-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 45275079 | 81% |
Reaction Steps
This compound was prepared from (4-chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine and 2,4-dichlorophenol in analogy to example 3. Chromatography on silica gel using ethyl acetate as an eluent gave the title compound as a colorless solid in 81% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389717B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-74f280c95bb44a3ea33a12e19e8d7c84 |
| Source note | uspto-grants-2013_03 |