HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxypyridine → HCID 59278669, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxypyridine | HCID 7971 | — |
| Reactant | (4-Chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine | HCID 86640783 | — |
| Product | HCID 59278669 | HCID 59278669 | — |
Reaction Steps
The title compound was prepared from (4-chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine and 3-hydroxypyridine in analogy to example 3. It was purified by column chromatography on Si—NH2 gel (Isolute) using ethyl acetate as eluent to give the title compound as a yellowish solid in 21% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389717B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-e83f15f9f6094c1da4b5d176b40d0003 |
| Source note | uspto-grants-2013_03 |