Glycolic Acid → HCID 86640095, compound

Participants

Reaction Conditions

Reaction Steps

Sitagliptin base (150 mg) was suspended in 2-propanol (2.5 mL). Glycolic acid (28 mg) was added and the mixture was stirred for one hour at ambient temperature and 2 hours at 40° C. to give a solution. The mixture was allowed to cool to ambient temperature and stirred for 24 hours at this temperature. The solution was concentrated under vacuum at ambient temperature.

Provenance & Evidence