HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → Propanoic acid, 2-bromo-3-(phenylmethoxy)-, methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(Benzyloxy)-2-bromopropanoic acid | HCID 10956265 | — |
| Product | Propanoic acid, 2-bromo-3-(phenylmethoxy)-, methyl ester | HCID 11011152 | 99% |
Reaction Steps
A solution of 2-bromo-3-[(phenylmethyl)oxy]propanoic acid (6 g, 23.2 mmol) in methanol (40 ml) at rt under argon was treated with thionyl chloride (1.7 ml, 23.2 mmol) and the reaction was then stirred at rt for 3 h and then evaporated to give product as a yellow oil (6.3 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389524B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-c81117c412504c65aeee6c5632869be6 |
| Source note | uspto-grants-2013_03 |