HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68598110, compound → 1,3-Dihydrofuro[3,4-c]pyridine-6-carboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68598110 | HCID 68598110 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1,3-Dihydrofuro[3,4-c]pyridine-6-carboxaldehyde | HCID 86642097 | 100% |
Reaction Steps
A solution of 1,3-dihydrofuro[3,4-c]pyridin-6-ylmethanol (66 mg, 0.437 mmol) in DCM (5 ml) at rt under argon was treated with manganese dioxide (380 mg, 4.37 mmol) and then stirred at rt for 2 h, filtered through a thin pad of Kieselguhr, eluting with DCM (40 ml) and methanol (10 ml), the organic extracts were evaporated to give the crude product as a brown oil (65 mg, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08389524B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-0cb9b937154b488a8d412fdf17e4cf57 |
| Source note | uspto-grants-2013_03 |