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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1943166Generated: October 30, 2026

HCID 68598110, compound → 1,3-Dihydrofuro[3,4-c]pyridine-6-carboxaldehyde

https://huagongshe.com/reaction/1943166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68598110HCID 68598110—
CatalystHCID 178418406HCID 178418406—
SolventDichloromethaneHCID 6344—
Product1,3-Dihydrofuro[3,4-c]pyridine-6-carboxaldehydeHCID 86642097100%

Reaction Steps

A solution of 1,3-dihydrofuro[3,4-c]pyridin-6-ylmethanol (66 mg, 0.437 mmol) in DCM (5 ml) at rt under argon was treated with manganese dioxide (380 mg, 4.37 mmol) and then stirred at rt for 2 h, filtered through a thin pad of Kieselguhr, eluting with DCM (40 ml) and methanol (10 ml), the organic extracts were evaporated to give the crude product as a brown oil (65 mg, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08389524B2
Source datasetuspto-grants-2013_03
ORD IDord-0cb9b937154b488a8d412fdf17e4cf57
Source noteuspto-grants-2013_03