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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 194322Generated: October 26, 2026

Dichloromethane → 4-(4-Chloro-2-fluoroanilino)-7-(2-(1,1-dioxothiomorpholino)ethoxy)-6-methoxyquinazoline

https://huagongshe.com/reaction/194322

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTributylphosphineHCID 13831—
Reactant1,1'-(Azodicarbonyl)dipiperidineHCID 73042—
Reactant4-(2-Hydroxyethyl)-1lambda~6~,4-thiazinane-1,1-dioneHCID 21874811—
Reactant4-(4-Chloro-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazolineHCID 135513720—
Product4-(4-Chloro-2-fluoroanilino)-7-(2-(1,1-dioxothiomorpholino)ethoxy)-6-methoxyquinazolineHCID 53793743—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-aed314ee4e55425a893a62ff592b7855
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)