反应详情

By the same method as in the step d) of Example 2, 2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-carbonitrile (7 mg, 0.043 mmol) was reacted with 3,5-dibromo-4-methoxy-benzoyl chloride (21 mg, 0.065 mmol) to obtain 1-(3,5-dibromo-4-methoxy-benzoyl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-carbonitrile as white solid (14.4 mg, 74%).