Sulfuric Acid → (3,5-Dibromo-4-hydroxy-phenyl)-(2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone sulfuric acid salt

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Reaction Steps

In a 25 ml flask, (3,5-dibromo-4-hydroxy-phenyl)-(2,3-dihydro-pyrido[4,3-b][1,4]oxazin-4-yl)-methanone (100 mg, 0.24 mmol) was suspended in tetrahydrofuran (8 ml) and the mixture was dissolved under heating. After cooling to room temperature, 1M sulfuric acid solution was added thereto dropwise. The formed solid was filtered to obtain the target compound 71 as white solid (78 mg, 69%).

Provenance & Evidence