HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(thiophen-2-yl)ethan-1-one → HCID 66863365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(thiophen-2-yl)ethan-1-one | HCID 2776372 | — |
| Reactant | N-[6-aminopyrid-3-yl]-5-fluoro-1-[(3-fluorophenyl)methyl]-1H-indole-2-carboxamide | HCID 66863527 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 66863365 | HCID 66863365 | 100% |
Reaction Steps
Compound 6 was prepared according to a process similar to that described in step 4.3, by reacting 0.1 g (0.26 mmol) of N-[6-aminopyrid-3-yl]-5-fluoro-1-[(3-fluorophenyl)-methyl]-1H-indole-2-carboxamide, prepared according to the protocol described in step 4.2, with 0.11 g (0.53 mmol) of 2-bromo-1-(thien-2-yl)ethanone in 4 mL of acetonitrile. 0.126 g of the expected product is thus obtained in the form of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394820B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-8c5f4c849e594af5822b2e30bb492495 |
| Source note | uspto-grants-2013_03 |