反应详情

Compound 16 was prepared according to a process similar to that described in step 15.3, by reacting 0.12 g (0.28 mmol) of N-[2-aminopyrid-4-yl]-5-trifluoromethyl-1-[(3-fluorophenyl)methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide, prepared according to the protocol described in step 15.2, with 0.084 g (0.56 mmol) of 3-bromobutan-2-one in 5 mL of acetonitrile. 45 mg of the expected product are obtained.

1. customprepared