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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1944029Generated: November 1, 2026

1-Ethynyl-4-fluorobenzene → {7-[4-(4-Fluoro-phenyl)-[1,2,3]triazol-1-yl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}-acetic acid

https://huagongshe.com/reaction/1944029

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-4-fluorobenzeneHCID 522627—
ReactantPropyl (7-azido-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetateHCID 59487226—
Product{7-[4-(4-Fluoro-phenyl)-[1,2,3]triazol-1-yl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl}-acetic acidHCID 46893930—

Reaction Steps

The title compound was prepared using procedures described in EXAMPLE 1 from propyl (7-azido-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetate and 1-ethynyl-4-fluorobenzene. MS (+ESI) m/z: 391.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08394819B2
Source datasetuspto-grants-2013_03
ORD IDord-03299a37e8cc4a9a816d0b52e4113dda
Source noteuspto-grants-2013_03