HCID 67074229, compound → HCID 67074723, compound

Participants

Reaction Steps

To a solution of (5R,6R,7S,8S)-6,7,8-tris-benzyloxy-5-[2-(4-methoxy-benzyl)-phenoxy]-4-oxa-spiro[2.5]octane (190 mg, 0.29 mmol) in methanol (5 ml) was added 10% Pd/C (60 mg) and stirred under hydrogen atmosphere at room temperature overnight. The reaction mixture was filtered through celite bed, washed with methanol (20 mL). The crude product was purified by preparative HPLC to furnish the title compound (22 mg).

Provenance & Evidence