Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Vanillin | HCID 1183 | — |
| Reactant | 2-Bromopropane | HCID 6358 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Isopropoxy-3-methoxybenzaldehyde | HCID 708253 | — |
Reaction Steps
A mixture of 4-hydroxy-3-methoxybenzaldehyde (100 g), potassium carbonate (182 g) and 2-bromopropane (81 ml) in DMF (500 ml) was stirred at 65° C. for 2 h. The reaction mixture was poured into water and extracted with ethyl acetate. The organic layer was washed with water and brine. The organic layer was dried (MgSO4), filtered and concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08394789B2 |
|---|
| Source dataset | uspto-grants-2013_03 |
|---|
| ORD ID | ord-ad006e3382e3496ea281420c13429fbb |
|---|
| Source note | uspto-grants-2013_03 |
|---|
