HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzophenone imine → Methyl 3-(diphenylmethyleneamino)-2-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzophenone imine | HCID 136809 | — |
| Reactant | Methyl 3-aMino-2-phenylpropanoate hydrochloride | HCID 42614489 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Methyl 3-(diphenylmethyleneamino)-2-phenylpropanoate | HCID 59563738 | — |
Reaction Steps
To methyl 3-amino-2-phenylpropanoate hydrochloride in CH2Cl2 was added benzophenone imine, and the solution was stirred overnight at room temperature. The mixture was then washed with H2O and the organics were dried (Na2SO4), filtered, and evaporated. Column chromatography (SiO2, 5-20% EtOAc/Hexanes) gave pure methyl 3-(diphenylmethyleneamino)-2-phenylpropanoate (E320).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08394826B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-938d2a8129c34bc79ac41b55f7bac6b8 |
| Source note | uspto-grants-2013_03 |